
For Payors
Nervana offers personalized support to help members understand symptoms and prevent flare-ups.
Why this matters
When symptoms persist after medical evaluation, members can bounce between tests, specialists, procedures, and online searching. Nervana offers a structured, non-pharmacologic support layer for people with persistent or medically-unexplained symptoms.
The experience is not limited to pain. Nervana supports patterns like GI symptoms, fatigue, headaches, sleep issues, and more.
Nervana explains neuroplastic symptoms in plain language so members can reduce fear and understand what they are practicing.
The app gives members a place to reflect, regulate, and respond to symptom spikes during the many days between visits.
Nervana provides portal access so teams can review engagement, symptom trends, and member-reported progress over time.
Research foundation
Groundbreaking research suggests that persistent symptoms can improve when care helps people reduce fear, reinterpret danger signals, process emotions, and practice safety.
JAMA Psychiatry
In a randomized clinical trial for primary chronic back pain, 66% of people receiving PRT were pain-free or nearly pain-free after treatment, with gains largely maintained at 1 year.
Read the PRT trialJAMA Network Open
A 2024 randomized trial for chronic musculoskeletal pain found EAET produced clinically significant pain reduction in 63% of participants, compared with 17% in CBT.
Read the EAET studyPain Reports
A randomized PSRT pilot for nonspecific chronic back pain found greater improvements in disability and pain bothersomeness than mindfulness-based stress reduction or usual care.
Read the PSRT studyWe translate clinical research into an easy-to-understand app.
Product walkthrough
See how Nervana turns education, guided practice, journaling, and coaching into a repeatable between-visit experience for chronic symptom support.
Meaningful results
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Helpful by session 10
85% of users find Nervana helpful by their 10th session.
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NPS score
We're proud people using Nervana would recommend it to family and friends.
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Symptom severity reduction
Average reported symptom severity reduction by week 5 of using the app.
Used by providers affiliated with


Arete HealthcarePARTNER WITH US
Nervana can complement care management, behavioral health, musculoskeletal, GI, headache, sleep, and whole-person health programs where chronic symptoms are part of the member journey.
Prevalence snapshot
Chronic symptoms are more common than you might think.
Estimated U.S. adult prevalence
Share your population, plan type, or program goals and the Nervana Team will follow up with a demo.